(1) Background: The constant technological progress, occurring sometimes at a rapid pace, can be challenging for some dentists, demanding significant additional effort to acquire knowledge and adapt to new techniques. New methods and materials should be implemented throughout the medical field, regardless of the specialty, from establishing the diagnosis using three-dimensional imaging to the actual endodontic treatment. (2) Methods: This cross-sectional study was designed to assess Romanian dentists’ use of modern endodontic techniques and materials through an online questionnaire targeting dentists who perform endodontic treatments as part of their clinical practice. The survey was conducted over seven months, from November 2022 to May 2023. (3) Results: 207 fully validated responses were obtained, resulting in a response rate of 69%. (4) Conclusions: Upon analysis of the questionnaire responses, a substantial proportion of medical professionals demonstrate openness to the utilization of contemporary technological advancements within the field of endodontics.