The etiology of malocclusions is multifactorial, with general somatic conditions, hereditary factors and the presence of behavioral disorders acting on their development and formation. Children with special needs develop vicious oral habits, which adversely affect the period of growth and development of both the jaws and the facial skeleton, as well as the soft tissues. Objective. The purpose of this study is to determine the prevalence of malocclusions in a group of children with special needs from Craiova, Romania. Materials and method. The study group comprised 286 special needs children, who were enrolled in a school from Craiova, Romania. Results. Following data collection and centralization, 56.29% of the subjects included in the study presented malocclusions, with female students being more affected than male students. Conclusions. Malocclusions among children with special needs have a higher prevalence. Thus, such patients require special oral care measures due to poor motor coordination, limited learning abilities and sensory problems.